{"id":15137,"date":"2018-03-30T19:02:57","date_gmt":"2018-03-30T19:02:57","guid":{"rendered":"https:\/\/www.golive.clarku.edu\/news\/2018\/03\/30\/clark-biology-professors-research-highlighted-in-nature-news\/"},"modified":"2025-05-19T09:53:39","modified_gmt":"2025-05-19T13:53:39","slug":"clark-biology-professors-research-highlighted-in-nature-news","status":"publish","type":"story","link":"https:\/\/www.clarku.edu\/news\/2018\/03\/30\/clark-biology-professors-research-highlighted-in-nature-news\/","title":{"rendered":"Clark biology professor\u2019s research highlighted in Nature News"},"content":{"rendered":"<p><html><body><\/p>\n<p><a href=\"https:\/\/www.nature.com\/\" target=\"_blank\" rel=\"noopener\">Nature<\/a>&nbsp;News recently highlighted research by&nbsp;<a href=\"https:\/\/www2.clarku.edu\/faculty\/facultybio.cfm?id=1103\">Nathan Ahlgren<\/a>, assistant professor of&nbsp;<a href=\"https:\/\/www2.clarku.edu\/departments\/biology\/\">biology<\/a>&nbsp;at Clark University, and his collaborators at the&nbsp;<a href=\"https:\/\/www.usc.edu\/\" target=\"_blank\" rel=\"noopener\">University of Southern California<\/a>.<\/p>\n<p>The March 19 article, titled&nbsp;<a href=\"https:\/\/www.nature.com\/articles\/d41586-018-03358-3\" target=\"_blank\" rel=\"noopener\">&ldquo;Machine learning spots treasure trove of elusive viruses: Artificial intelligence could speed up metagenomic studies that look for species unknown to science,<\/a>&rdquo; focuses on research that Ahlgren began as a postdoctoral research associate in USC&rsquo;s Department of Biological Sciences, working with&nbsp;Jie Ren, then a graduate student and now a postdoctoral computational biologist at USC.<\/p>\n<figure id=\"attachment_457\" aria-describedby=\"caption-attachment-457\" style=\"width: 300px\" class=\"wp-caption alignright\"><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-457\" src=\"https:\/\/www.clarku.edu\/news\/wp-content\/uploads\/sites\/37\/virus-sybrgreentag-usc-jed-fuhrman-lab-clark-university-300x205-2.jpg\" alt=\"Fluorescence micrograph of prokaryotes and viruses stained green\" width=\"300\" height=\"205\"><figcaption id=\"caption-attachment-457\" class=\"wp-caption-text\">Fluorescence micrograph of prokaryotes and viruses stained green <a href=\"https:\/\/dornsife.usc.edu\/labs\/fuhrmanlab\/gallery\/\" target=\"_blank\" rel=\"noopener\">Fuhrman Lab<\/a>)<\/figcaption><\/figure>\n<p>Ahlgren is continuing this research as part of a four-year, $1.5 million&nbsp;<a href=\"https:\/\/www.nih.gov\/\" target=\"_blank\" rel=\"noopener\">National Institutes of Health<\/a>&nbsp;grant, titled&nbsp;<a href=\"https:\/\/www.nigms.nih.gov\/Research\/specificareas\/MIDAS\/Pages\/res-project-grants-r01s.aspx\" target=\"_blank\" rel=\"noopener\">&ldquo;Computational Studies of Virus-host Interactions Using Metagenomics Data and Applications,<\/a>&rdquo; with his co-principal investigator,&nbsp;<a href=\"http:\/\/pressroom.usc.edu\/fengzhu-sun\/\" target=\"_blank\" rel=\"noopener\">Fengzhu Sun<\/a>, professor of biological sciences and mathematics, and his former adviser,&nbsp;<a href=\"https:\/\/dornsife.usc.edu\/cf\/faculty-and-staff\/faculty.cfm?pid=1003269\" target=\"_blank\" rel=\"noopener\">Jed Fuhrman<\/a>, professor of biological sciences, both of USC.&ldquo;This grant involves developing statistical and computational tools to identify and characterize new viruses that could help us better understand human health, especially viruses that infect bacteria in our intestines,&rdquo; Ahlgren says.<\/p>\n<p>The Nature News article describes how the USC research team &ndash; which included Ahlgren &ndash; used algorithms in machine learning, a type of artificial intelligence, to identify previously unknown species of viruses, separate from the bacteria that are also present with viruses.<\/p>\n<p>&ldquo;In any setting, there will be bacteria, and viruses infecting those bacteria, so when we get DNA sequences from a sample, we get sequences of bacteria and viruses at the same time. We&rsquo;re trying to distinguish the two,&rdquo; Ahlgren explains. &ldquo;We built a machine learning tool that distinguishes these DNA sequences &ndash; it&rsquo;s a kind of categorizing tool.&rdquo;<\/p>\n<p>&ldquo;Previously, people had no method to study viruses well,&rdquo; Ren tells&nbsp;Nature News.<\/p>\n<p>The Nature News report references a 2017 Microbiome journal paper by Ren, Ahlgren, and three other scientists, titled&nbsp;<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28683828\" target=\"_blank\" rel=\"noopener\">&ldquo;VirFinder: a novel k-mer based tool for identifying viral sequences from assembled metagenomic data.<\/a>&#8220;<\/body><\/html><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Nature&nbsp;News recently highlighted research by&nbsp;Nathan Ahlgren, assistant professor of&nbsp;biology&nbsp;at Clark University, and his collaborators at the&nbsp;University of Southern California. The March 19 article, titled&nbsp;&ldquo;Machine learning spots treasure trove of elusive viruses: Artificial intelligence could speed up metagenomic studies that look for species unknown to science,&rdquo; focuses on research that Ahlgren began as a postdoctoral research [&hellip;]<\/p>\n","protected":false},"featured_media":15138,"template":"","meta":{"story_color":"#525250","story_headerImg":15138,"section_label":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[227],"displayed_author":[242],"featured":[],"topic":[244,247,366,150,160,192,162],"class_list":["post-15137","story","type-story","status-publish","has-post-thumbnail","hentry","category-science-technology","displayed_author-meredith-woodward-king","topic-biology","topic-books-and-publications","topic-doctoral-programs","topic-faculty","topic-faculty-research","topic-health-and-disease","topic-research"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.2 (Yoast SEO v27.3) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Clark biology professor\u2019s research highlighted in Nature News | ClarkU News<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.clarku.edu\/news\/2018\/03\/30\/clark-biology-professors-research-highlighted-in-nature-news\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Clark biology professor\u2019s research highlighted in Nature News\" \/>\n<meta property=\"og:description\" content=\"Nature&nbsp;News recently highlighted research by&nbsp;Nathan Ahlgren, assistant professor of&nbsp;biology&nbsp;at Clark University, and his collaborators at the&nbsp;University of Southern California. 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