Dr. Jeffrey Gustafson, Ph.D.
Assistant Professor of Organic Chemistry
San Diego State University Gustafson Group Website
“The no spin zone: Atropisomerism as a an inspiration for drug design and new chemistry”
Atropisomerism is a type of chirality that is ubiquitous but often overlooked in modern drug discovery. In this talk we discuss studies on leveraging atropisomerism as a design principle in medicinal chemistry, and how this work led to several seemingly disparate projects that began due to synthetic challenges associated with accessing pharmaceutically relevant atropisomers.