Publications

Formation and Growth of Oligomers: A Monte Carlo Study of an Amyloid Tau Fragment.          

 PLoS Comput. Biol. 4(12), e1000238, 2008.                                                                                                                                       

D. Li, S. Mohanty, A. Irbäck, S. Huo                                                                                                                                                 

 

A Novel Mutant Cardiac Troponin C Disrupts Molecular Motions Critical for Calcium Binding Affinity and Cardiomyocyte Contractility.            

Biophysical J. 94, 3577-3589. 2008. (On the Cover of May 1st issue)                                                                                        

C. Lim, H. Yang, M. Yang, C. Wang, J. Shi, E. A. Berg, D. R. Pimentel,  J. K. Gwathmey, R. J. Hajjar, M. Helmes, C. Costello, S. Huo, R. Liao

Predicting the Folding Pathway of Engrailed Homeodomain with a Probabilistic Roadmap Enhanced Reaction-path Algorithm.                                                                                                                                    

Biophysical J. 94, 1622-1629, 2008.                                                                                                                                          

D. Li, H. Yang, L. Han, S. Huo

 

Evaluation of Configurational Entropy Methods from Peptide Folding-Unfolding Simulation.                   

J. Phys. Chem. B. 111:13807-13813, 2007.                                                                                                                                   

D. Li, M. Khanlarzadeh, J. Wang, S. Huo, R. Brüschweiler

 

Structural and Pathway Complexity of β-strand Reorganization within Aggregates of Human Transthyretin(105-115) Peptide.

J. Phys. Chem. B. 111: 5425-5433, 2007.

D. Li, L. Han, S. Huo 

 

Temperature-Dependent Probabilistic Roadmap: Algorithm for Calculating Variationally Optimized Conformational Transition Pathways.

J. Chem. Theory Comput. 3: 17-25, 2007.

H. Yang, H. Wu, D. Li, L. Han, S. Huo 

 

Sequence-Dependent Unfolding Pathway Plays a Critical Role in the Amyloidogenicity of Transthyretin.

Biochemistry. 45: 11992-12002, 2006.

M. Yang, B. Yordanov Y. Levy, R. Brüschweiler, and S. Huo 

 

Potential Influence of Asp in the Ca2+ Coordination Position 5 of Parvalbumin on the Calcium Binding Affinity: A Computational Study.

J. Inorg. Biochem. 100: 1879–1887, 2006.

J. Zhao, D. J. Nelson, S. Huo 

 

Peptide Plane Can Flip in Two Opposite Directions: Implication in Amyloid Formation of Transthyretin.

J. Phys. Chem. B. 110: 5829-5833, 2006.

M. Yang, M. Lei, B. Yordanov, S. Huo 

  

Initial Conformational Changes of Human Transthyretin under Partially Denaturing Conditions.

Biophysical J. 89: 433-443, 2005.

M. Yang, M. Lei, R. Bruschweiler, S. Huo 

 

Intrinsic versus Mutation Dependent Instability/flexibility: A Comparative Analysis of the Structure and Dynamics of Wild-type Transthyretin and its Pathogenic Variants.

J. Struct. Biol. 148: 153-168, 2004.

M. Lei, M. Yang, S. Huo 

 

Why is Leu55 ® Pro55 Transthyretin Variant the Most Amyloidogenic: Insight from Molecular dynamics Simulations of Transthyetin Monomers.

Protein Sci. 12: 1222-1231, 2003.

M. Yang, M. Lei, S. Huo

 

Computational Alanine Scanning of the 1:1 Human Growth Hormone-Receptor Complex.

J. Comput. Chem. 23: 15-27, 2002.

S. Huo,  I. Massova, P.A. Kollman 

  

The MaxFlux Algorithm for Calculating Variationally Optimized Reaction Paths for Conformational Transitions in Many Body Systems at Finite Temperature

J. Chem. Phys., 107: 5000-5006, 1997.

S. Huo, J. E. Straub