Recent Honors Thesis Titles
2005
Elysia Alvarez Honors advisor: D. Nelson
Computational Analysis of the Interaction of the Anthrax Lethal Factor Exotoxin with Peptide
Substrate Analogs and with the anthrax Protective Antigen "Pre-Pore"
Mary Badon Honors advisors: D. Larochelle (Clark),
C. Field and T. Mitchison (Harvard Medical School)
Analysis of Centrosome Function in Cell Division and Characterization of Small Molecule Inhibitors
Kim Leblanc Honors advisor: UMass
Attachment of the Lyme Disease Spirochete to Mammalian Host Cells as Mediated by BBK032
Adam McPherson Honors advisor: UMass
Analysis of factors associated with Pbp1p in the post-transcriptional control of gene expression
Nicole Mills Honors advisor: J. Thackeray
Knocking out a Potential Tyrosine Phosphorylation Site in Drosophila PLC-gamma
James Vecchione Honors advisor: D. Larochelle
Understanding the Pats1 Gene and its Involvement in the Molecular Regulation of Cytokinesis
Boyan Yordanov Honors advisor: S. Huo
Initial conformational changes of transthyretin triggering amyloid formation: Molecular dynamics simulation under low pH conditions
2004
Juliana DeMelfi Honors advisor: UMass
An Analysis of EBV-Specific CD8+ T Cell Receptor Repertoire Interactions with an HLA-A*0201 / BMLF-1 Epitope
Kriti Gaur Honors advisor: D. Robertson
Characterization of enzyme Glutamine Synthetase in the dinoflagellate Alexandrium tamerense
Stephanie Roy Honors advisor: D. Nelson
Docking of 3Õ-deoxy-ATP into the Adenylyl Cyclase Active Site of Wild-Type and Mutant Anthrax Edema Factor Variants:
An Analysis Utilizing GRID-21, Simple Molecular Mechanics with InsightII and GRASP Surface Electrochemical Potential.
Zu Shen Honors advisor: D. Thurlow
Kinetic Studies of ATP/CTP tRNA Nucleotidyltransferase from M. jannaschi
Miguel Stein Honors advisor: D. Robertson
Effects of Extracellular Nitrate on the Regulation of Glutamine Synthatase II2 in Skeletonema Costatum
2003
Sarah Deroko Honors advisor: D. Larochelle
Characterization of Pats1, a novel gene required for cytokinesis in Dictyostelium
Matthew Evans Honors advisor: UMass
Identification of Point Mutants in Pab1p that Specifically Eliminate Interaction with the Positive Activator of Poly(A) Nuclease, Pan3p
Jinal Patel Honors advisor: D. Thurlow
A kinetic study of the Drosophila melanogaster whole and truncated CCA-adding enzymes
Branka Stancevic Honors advisor: D. Thurlow
Site-directed mutagenesis of M. janaschii ATP/CTP tRNA nucleotidyltransferase
Bradford Stanley Honors advisor: Stryker Biotech
Uncovering the Origins of Heterogeneity in a Recombinant Protein Product: Analysis of recombinant human Osteogenic Protein-1
by two-dimensional gel electrophoresis
2002
Nate Agrin Honors advisor: UMass
Mapping Protein Interactions in the Regulatory Network Controlling Pab1p-Dependant Poly(A) Nuclease
Megan Albert Honors advisor: D. Thurlow
Mutants and models of nucleotidyltransferase
Lored Asllani Honors advisor: D. Thurlow
Purification of tRNA nucleotidyltransferase for structural studies
Frances Austin Honors advisor: J. Thackeray
Screening for Genes on the X-Chromosome Affecting Geotaxis in Drosophila melanogaster
Nathan Berkowitz Honors advisor: D. Hibbett
RT-PCR Amplification of Fungal Mn Peroxidase mRNAs for Phylogenetic Studies
Jennifer Pacheco Honors advisor: UMass
RNA Recognition Motifs in Overexpression of Yeast Poly (A)-Binding protein
Erika Person Honors advisor: D. Nelson
Molecular dynamics of single-site variants of Human superoxide dismutase linked to Lou GehrigÕs Disease
Craig Stone Honors advisor: UMass
Mechanism of Early Endosome Tethering by Rab 5, EEA1, and PtdIns(3)P
Joshua Suhl Honors advisor: J. Thackeray
Mutating the PLC-gamma SH2 domains in Drosophila melanogaster
2001
Kamau Fahie Honors advisor: D. Nelson
Molecular dynamics simulation analysis of the metal binding properties of a non-conservative mutational variant
of the Silver Hake parvalbumin (Isoform B) whole protein and functional fragments
Nyawira Gikunju Honors advisor: D. Thurlow
Site-directed mutagenesis of the ATP/CTP:tRNA nucleotidyltransferase in the yeast Saccharomyces cerevisiae
Christine Whittish Honors advisor: UMass
Does Bloom Syndrome Helicase Affect Class Switch Recombination?