Undergraduate Research
Honors Theses
2009
Timothy Hanley – "Drug Resistance in a Haploid Vertebrate
Cell Line"
Dushani Palliyaguru – "Insulin Receptor Substrate 2 (IRS-2)
Regulates Apelin Gene Expression in Mammary Tumor Cell Lines"
2008
Shymal Asher – "Is N Terminal Dimerization of HSP90 Necessary for Function?"
Saima Chaudhry – "Elucidation of the Folding and Aggregation of the Amyloid ?-Protein by Diglycine Scanning Mutagenesis"
Daniel Hidalgo – "Characterization of a new PLC-gamma Mutation in Drosophila melanogaster"
Lincoln Muhoro – "Structural Basis of Epidermolysis Bullosa (EB): Insights from Biophysical Studies of Keratin Intermediate Filament (KIF) Peptides"
2007
Dan Adams – "Dictyostelium discoideum CenB: A Mutational
Analysis"
Darryl Aucoin – "On the Folding of Islet Amyloid Polypeptide
(IAPP) in Water"
Sara McNiff – "Site Directed Mutagenesis, Expression, and Characterization of a K154R Mutant of Lysyl Oxidase"
Academic Spree Day Presentations
2009
Lisa Crislip '09 – "Chimeric primase-helicases in mitochondrial DNA replication" (in collaboration with Jamie Towle, graduate student; sponsor: Professor Donald Crampton)
Mary Abdalla '09 and Yennhi Nguyen '09 –"Discovery of Bacteriophage specific for Streptococcus mutans" (sponsor: Professor Donald Crampton)
Chatura Jayakody '10 – "Insight into protein purification" (sponsor: Professor David Thurlow)
Molly Brennan '09 – "Effects of neonatal tactile stimulation on social behavior" (sponsors: Professor David Thurlow, Clark U. and Dr. Jun Xu, Tufts Veterinary School of Medicine)
2008
Laura Andersh '08 – "Characterizing the structure/function of Glut1 using Factor Xa Proteolysis" (in collaboration with Julie De Zutter, graduate student; sponsors: Professor David Thurlow, Clark U. and Anthony Carruthers, UMass Medical School)
Laura Andersh '08 – "Cloning, expression, and purification of LMA glycoprotein" (sponsor: Professor David Thurlow)
Annette Nelkenbaum '09 – "Metastasis in liver cancer" (sponsors: Professor David Thurlow, Clark U. and Brian Lewis, UMass Medical School)
Dushani Palliyaguru '09 – "Role of insulin receptor protein-2 (IRS-2) in regulation of apelin in breast cancer metastasis" (sponsors: Professor David Thurlow, Clark U. and Leslie Shaw, UMass Medical School)
Shymal Asher '08 – "Is N-terminal dimerization of Hsp90 necessary for its function?" (sponsors: Profesor Daivd Thurlow, Clark U. and Dan Bolon, UMass Medical School)
Lincoln Muhoro '08 – "Oligosaccharide assay precision on mAb1 and evaluation of CEM microwave technology" (sponsors: Professor David Thurlow, Clark U. and David Ouellette, Abbott Bioresearch Center)
2007
Dan Adams '07 – "Mutational analysis of Dictyostelium centrin B" (in collaboration with Sebastian Mana-Capelli, graduate student; sponsor: Professor Denis Larochelle)
Fall Fest Presentations
2008
Dmitry Merzon '09 – "Antibodies as tools to study Fanconi Anemia" (sponsors: Professor David Thurlow, Clark U. and Alan D’Andrea, Dana Farber Cancer Institute)
Chatura Jayakody '10 – "Purification of protein of interest" (sponsors: Professor David Thurlow, Clark U. and Scott Gridley, BlueSky Biotech)
Annette Nelkenbaum '09 – "The effects of tumor suppressor gene p16INK4a on transformation phenotypes in HCC" (sponsors: Professor David Thurlow, Clark U. and Brian Lewis, UMass)


