Undergraduate Research
Honors Theses
2012
Jenni Adams - "Understanding the function of KIFAP3 and its possible role in ALS"
Jennifer Gaines - "Study of the Self-Assembly of the Amyloid-B42 Protein in the presence of Rifamycin SV"
Abhijit Srungavarapu - "Gene Delivery VIA Funtionalized Poly(Ethylene Imine)-DNA Poly- Plexes"
2011
Priyanka Kapur – "RBP Mediated
Post-Transcriptional Regulation of Nitrate Reductase in Thalassiosira
pseudonana"
Jason Lui –
"Characterization of D. discoideum Rad4"
2010
Jasmin Abraham –
"Biochemical and Genetic Analysis of Octopamine Biosynthesis"
Di Deng – "The Role of
Stomatin in GluT1 Function and Regulation"
Tara Deveraj – "Histone
Deacetylase Inhibitors SAHA and MS-275 Differentially Induce Survival Motor
Neuron 2 Gene Expression"
2009
Timothy Hanley – "Drug Resistance in a Haploid Vertebrate
Cell Line"
Dushani Palliyaguru – "Insulin Receptor Substrate 2 (IRS-2)
Regulates Apelin Gene Expression in Mammary Tumor Cell Lines"
2008
Shymal Asher – "Is N Terminal Dimerization of HSP90 Necessary for Function?"
Saima Chaudhry – "Elucidation of the Folding and Aggregation of the Amyloid ?-Protein by Diglycine Scanning Mutagenesis"
Daniel Hidalgo – "Characterization of a new PLC-gamma Mutation in Drosophila melanogaster"
Lincoln Muhoro – "Structural Basis of Epidermolysis Bullosa (EB): Insights from Biophysical Studies of Keratin Intermediate Filament (KIF) Peptides"
Academic Spree Day Presentations
2012
Jenni Adams '12 - Cloning and Cellular Characterization of KIFAP3 Splice Isoforms (in collaboration with Matt Stigliano, graduate student, UMASS Medical School; Sponsors Professor David Thurlow, Clark University & Professor John Landers UMASS Medical School)
Jennifer Gaines '12 - NMR Studies of Amyloid Beta Protein Aggregation in the Presence of Rifamycin SV (sponsor: Professor Noel Lazo)
Abhijit Srungavarapu '12 - New gene delivering polymers based on PEI copolymers modified via "click chemistry" (in collaboration with Robert P. Doyle, graduate student; sponsor: Professor David Thurlow)
2011
Jenni Adams '12 – "ALS and the
Search for a KIFAP3 Interaction Protein (sponsor: Professor John Landers
[UMass Medical School] and Professor David Thurlow)
Kristen Murrone '11 – "Sentinel
Events Model: Phase 3 Study at UMass Medical School" (sponsor:
Professor David Thurlow)
Abhijit Srungavarapu '12 –
"G-Priming Activity of the Primase T7 Chimera" (sponsor: Professor David
Thurlow, and in collaboration with Jamie Towle, graduate student)
Dan Moynihan '11 – "Biophysical
Studies of the Effects of the Italian Mutation on the Self-Assembly of the
Amyloid-β Protein" (sponsor: Professor Noel
Lazo)
Jason Lui '11 – "Knockout of Rad4
DNA Repair Gene in Dictyostelium discoideum" (sponsor: Professor
Denis Larochelle)
2010
Kyle Denton '11 –
"Development of a Genetic System for Denitrovibrio acetiphilus
(sponsor: Professor Heather Wiatrowski)
Serena Pham '11 –
"Biogenic Amines-Gated Chloride Channels' Roles in C. elegans Behaviors
(sponsor: Professor Noel Lazo)
Corri Stewart '10 – "A
Comparison of Mercury and Chromate Responses in Shewanella Pmeodemsos
(MR-1) (sponsor: Professor Heather Wiatrowski)
2009
Lisa Crislip '09 – "Chimeric primase-helicases in mitochondrial DNA replication" (in collaboration with Jamie Towle, graduate student; sponsor: Professor Donald Crampton)
Mary Abdalla '09 and Yennhi Nguyen '09 –"Discovery of Bacteriophage specific for Streptococcus mutans" (sponsor: Professor Donald Crampton)
Chatura Jayakody '10 – "Insight into protein purification" (sponsor: Professor David Thurlow)
Molly Brennan '09 – "Effects of neonatal tactile stimulation on social behavior" (sponsors: Professor David Thurlow, Clark U. and Dr. Jun Xu, Tufts Veterinary School of Medicine)
2008
Laura Andersh '08 – "Characterizing the structure/function of Glut1 using Factor Xa Proteolysis" (in collaboration with Julie De Zutter, graduate student; sponsors: Professor David Thurlow, Clark U. and Anthony Carruthers, UMass Medical School)
Laura Andersh '08 – "Cloning, expression, and purification of LMA glycoprotein" (sponsor: Professor David Thurlow)
Annette Nelkenbaum '09 – "Metastasis in liver cancer" (sponsors: Professor David Thurlow, Clark U. and Brian Lewis, UMass Medical School)
Dushani Palliyaguru '09 – "Role of insulin receptor protein-2 (IRS-2) in regulation of apelin in breast cancer metastasis" (sponsors: Professor David Thurlow, Clark U. and Leslie Shaw, UMass Medical School)
Shymal Asher '08 – "Is N-terminal dimerization of Hsp90 necessary for its function?" (sponsors: Profesor Daivd Thurlow, Clark U. and Dan Bolon, UMass Medical School)
Lincoln Muhoro '08 – "Oligosaccharide assay precision on mAb1 and evaluation of CEM microwave technology" (sponsors: Professor David Thurlow, Clark U. and David Ouellette, Abbott Bioresearch Center)
Fall Fest Presentations
2010
Hakeem Hindi '11 - Elucidation of Amyloid-beta Protein Folding and Self-assembly by Studies of Double Mutants. (sponsor: Professor Noel Lazo)
Jon Imeraj '11 and Maria Luisa Sandoval '11 - Expression of Lysyl Oxidase in E. coli. (sponsor: Professor Frederick Greenaway)
Craig Jeskey '11 - Cloning Single-Stranded DNA Protein For in vitro Replisome Reconstruction. (in collaboration with: Jamie Towle, graduate student; sponsor: Professor Donald Crampton)
Priyanka Kapur '11 - Post-Transcriptional Gene Regulation of Marine Diatoms. (sponsor: Professor Deborah Robertson)
Sang A. Kim '11 - Inhibition of Amyloid-beta aggregation with small molecules: mechanistic studies. (in collaboration with: Kevin Robbins, graduate student; sponsor: Professor Noel Lazo)
Abhijit Srungavarapu '12 - Ion transport through polymer matrices: towards more efficient rechargeable lithium batteries. (sponsor: Professor Sergio Granados-Focil)
2009
Kyle Denton '10 –
"Identification of an Unknown Anaerobic Bacteria" (sponsor: Professor
Heather Wiatrowski
Corri Stewart '10 – "Growth
Trends in Shewanella Oneidensis in Potassium Chromate and Mercuric
Chloride (sponsor: Professor Heather Wiatrowski)
2008
Dmitry Merzon '09 – "Antibodies as tools to study Fanconi Anemia" (sponsors: Professor David Thurlow, Clark U. and Alan D’Andrea, Dana Farber Cancer Institute)
Chatura Jayakody '10 – "Purification of protein of interest" (sponsors: Professor David Thurlow, Clark U. and Scott Gridley, BlueSky Biotech)
Annette Nelkenbaum '09 – "The effects of tumor suppressor gene p16INK4a on transformation phenotypes in HCC" (sponsors: Professor David Thurlow, Clark U. and Brian Lewis, UMass)